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[去铁胺治疗含铁血黄素沉着症。持续皮下输注期间的粪便铁排泄]

[Deferoxamine in hemosiderosis. Fecal iron excretion during continuous subcutaneous infusion].

作者信息

Krüger N, Kijewski H, König R, Tillmann W, Schröter W

出版信息

Dtsch Med Wochenschr. 1984 Nov 2;109(44):1682-5. doi: 10.1055/s-2008-1069435.

Abstract

Faecal iron excretion during continuous subcutaneous deferoxamine infusion was measured by flameless atom-absorption spectral photometry in 21 patients with homozygous ss-thalassaemia and one patient with Blackfan-Diamond anaemia. Taking into account faecal and urinary iron excretion, more iron was eliminated than was taken up during transfusion and by intestinal absorption. Urine contained 37.9%, faeces 62.1% of the amount of iron eliminated.

摘要

采用无焰原子吸收光谱光度法,对21例纯合子ss-地中海贫血患者和1例布莱克范-戴蒙德贫血患者在持续皮下输注去铁胺期间的粪便铁排泄情况进行了测定。综合考虑粪便和尿液中的铁排泄量,发现排出的铁量超过了输血和肠道吸收所摄取的铁量。尿液中的铁排泄量占总铁排泄量的37.9%,粪便中的铁排泄量占62.1%。

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