Herbuté S, Pintat R, Ramade F, Baylé J D
Gen Comp Endocrinol. 1984 Oct;56(1):1-8. doi: 10.1016/0016-6480(84)90054-6.
Exposure of control quail to low ambient temperature (4 degrees) for a short duration (15 min) led to a rapid increase in plasma thyroxine (T4) levels. A peak appeared 40 min after the cold began and was followed by a progressive and slow decline. T4 levels were elevated in birds maintained for up to 3 hr at 4 degrees. Restraint stress could be accompanied by a slight and late decrease in thyroxine concentration, indicating that glucocorticoids could partly inhibit thyroid function. Both cold and restraint stresses elicited sustained adrenocortical activation. No thyroid response to cold appeared after complete or partial neural deafferentation of the hypothalamus, indicating that cold signals were conveyed to the thyrotropic centers from peripheral and/or deep thermoreceptors through neural posterior-lateral afferents to the hypothalamus. No thalamic relay appeared to be necessary since normal thyroidal stimulation was observed after thalamic-hypothalamic disconnection. Such a response persisted in hemispherectomized quail.
将对照鹌鹑短时间（15分钟）暴露于低温环境（4摄氏度）会导致血浆甲状腺素（T4）水平迅速升高。寒冷开始40分钟后出现峰值，随后逐渐缓慢下降。在4摄氏度下维持长达3小时的鸟类，其T4水平升高。束缚应激可能伴随着甲状腺素浓度轻微且延迟的下降，这表明糖皮质激素可能部分抑制甲状腺功能。寒冷和束缚应激均引发持续的肾上腺皮质激活。下丘脑完全或部分神经去传入后，未出现对寒冷的甲状腺反应，这表明寒冷信号通过神经后外侧传入纤维从外周和/或深部温度感受器传递至促甲状腺素中心，再到下丘脑。丘脑-下丘脑断开连接后观察到正常的甲状腺刺激，这表明似乎不需要丘脑中继。这种反应在大脑半球切除的鹌鹑中持续存在。
