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[膀胱癌的辅助局部阿霉素治疗]

[Adjuvant topical doxorubicin therapy in bladder cancer].

作者信息

Vecsey D, Pánykó E

出版信息

Fortschr Med. 1984 Sep 27;102(36):909-12.

PMID:6489904
Abstract

Thirty-four patients with tumors of the bladder were, after prior tumor surgery, treated with topical doxorubicin. Owing to undesired side effects, it was possible to adhere to the treatment regime in only 30 of the patients. Over an average observation period of 18 months, the number of recurrent lesions had diminished; the number of tumor-free patients at the time of evaluation was high. In view of these results, the question may be asked: could this form of treatment possibly be a suitable alternative to cystectomy, which has such a negative effect on the patient's quality of life? The answer can be given only on the basis of further prospective studies.

摘要

34例膀胱肿瘤患者在先前的肿瘤手术后接受了局部阿霉素治疗。由于出现了不良副作用,只有30例患者能够坚持治疗方案。在平均18个月的观察期内,复发病变的数量有所减少;评估时无肿瘤患者的数量很多。鉴于这些结果,可能会提出这样一个问题:这种治疗方式能否成为对患者生活质量有如此负面影响的膀胱切除术的合适替代方案?只有在进一步的前瞻性研究基础上才能给出答案。

相似文献

1
[Adjuvant topical doxorubicin therapy in bladder cancer].[膀胱癌的辅助局部阿霉素治疗]
Fortschr Med. 1984 Sep 27;102(36):909-12.
2
The effect of cystectomy, and perioperative methotrexate, vinblastine, doxorubicin and cisplatin chemotherapy on the risk and pattern of relapse in patients with muscle invasive bladder cancer.膀胱切除术以及围手术期使用甲氨蝶呤、长春花碱、阿霉素和顺铂化疗对肌层浸润性膀胱癌患者复发风险及复发模式的影响。
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[Adjuvant topical chemotherapy with cisplatin in superficial bladder cancer].[顺铂辅助局部化疗用于浅表性膀胱癌]
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[Local mitomycin-C therapy of infiltrating bladder cancer].[浸润性膀胱癌的局部丝裂霉素 C 治疗]
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Use of mitomycin as prophylaxis following endoscopic resection of superficial bladder cancer.丝裂霉素在内镜下切除浅表性膀胱癌后作为预防用药的应用。
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[Results of radical cystectomy for management of invasive bladder cancer with special reference to prognostic factors and quality of life depending on the type of urinary diversion].[根治性膀胱切除术治疗浸润性膀胱癌的结果,特别提及根据尿流改道类型的预后因素和生活质量]
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Intravesical instillation of bacille Calmette-Guérin for superficial bladder cancer: cost-effectiveness analysis.卡介苗膀胱内灌注治疗浅表性膀胱癌的成本效益分析。
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Proton beam therapy for invasive bladder cancer: a prospective study of bladder-preserving therapy with combined radiotherapy and intra-arterial chemotherapy.质子束疗法治疗浸润性膀胱癌:一项联合放疗和动脉内化疗的保膀胱治疗前瞻性研究。
Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1371-9. doi: 10.1016/j.ijrobp.2005.10.023.
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[Prevention of the recurrence of bladder tumors with local adriamycin therapy].[局部应用阿霉素治疗预防膀胱肿瘤复发]
Orv Hetil. 1984 Oct 7;125(41):2503-6.

引用本文的文献

1
Local adriamycin treatment for prevention of recurrence of superficial bladder tumours.局部阿霉素治疗预防浅表性膀胱肿瘤复发
Int Urol Nephrol. 1988;20(6):611-5. doi: 10.1007/BF02549493.