Jones D E, Russo J F, Dombroski R A, Lentz S S
J Adolesc Health Care. 1984 Oct;5(4):243-7. doi: 10.1016/s0197-0070(84)80125-4.
Three hundred and eleven adolescent patients with abnormal Pap smears were referred for evaluation. Two hundred and ninety-three were evaluated with colposcopy and directed biopsies. Fourteen percent had normal findings, 42% CIN I, 22% CIN II, and 22% CIN III. The distribution of pathologic findings was similar to that in an adult population in the same clinic except that no invasive carcinomas were found in our adolescents. Since there was a predominance of exocervical lesions, only 3% of the patients required diagnostic conization. Ninety-four percent of the adolescents were treated by cryotherapy as compared to 68% of the adults. Since adolescents have significant cervical intraepithelial neoplasia, an abnormal Pap smear should be evaluated and a tissue diagnosis obtained. Outpatient therapy is well suited for the majority of teenagers because the lesions are commonly confined to the exocervix.
311例巴氏涂片异常的青少年患者被转诊进行评估。293例接受了阴道镜检查和定向活检。14%检查结果正常，42%为CIN I，22%为CIN II，22%为CIN III。病理结果分布与同一诊所成年人群相似，只是在我们的青少年患者中未发现浸润癌。由于宫颈外病变占主导，仅3%的患者需要诊断性锥切术。94%的青少年接受了冷冻治疗，而成人接受冷冻治疗的比例为68%。由于青少年存在显著的宫颈上皮内瘤变，巴氏涂片异常时应进行评估并获得组织诊断。门诊治疗非常适合大多数青少年，因为病变通常局限于宫颈外口。
