Ejaculatory inhibition with trazodone.

The case of a middle-aged depressed man who experienced ejaculatory inhibition after being treated with trazodone is presented. A discussion of the probable mechanism involved in causing this side effect is included, as well as a review of other side effects of trazodone on the genitourinary system. Other medications with genitourinary sequelae are reviewed. Such complications may deter patient compliance. It is recommended that clinicians carefully screen for iatrogenic disturbances in sexual function.