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[子宫内膜癌的预后因素及治疗指征]

[Prognostic factors in cancer of the endometrium and therapeutic indications].

作者信息

Fossat C, Mage P, Marée D, Avril A, Pigneux J, Richaud P

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1984;13(5):573-8.

PMID:6491199
Abstract

Between 1970 and 1979, 270 patients were treated at Fondation Bergonie for carcinoma of the endometrium (169, for the whole treatment). The cases were classified according to the FIGO staging system. The mean age of the patients was 62.2, with a range from 31 to 95. 62% of patients had stage I carcinoma, 16% stage II, 18% stage III and 4% stage IV. The operability rate, according to the patients ages was considered a main factor in the prognosis. The 5 years survival was 64% for stage I, 60% for stage II, 47% for stage III and 0% for stage IV. Histologic grade of the tumor and depth of myometrial invasion are also important prognosis factors; both influencing survival. This study compared with others, provides the main prognosis factors: age and operability, stage of the tumor, histologic grade, depth of myometrial invasion and pelvic and/or para-aortic lymph nodes involvement. The authors conclude by specifying the indications for treatment.

摘要

1970年至1979年间,270例子宫内膜癌患者在贝贡尼基金会接受治疗(其中169例接受了全程治疗)。病例根据国际妇产科联盟(FIGO)分期系统进行分类。患者的平均年龄为62.2岁,范围在31岁至95岁之间。62%的患者为I期癌,16%为II期,18%为III期,4%为IV期。根据患者年龄判断的可手术率被认为是预后的一个主要因素。I期患者的5年生存率为64%,II期为60%,III期为47%,IV期为0%。肿瘤的组织学分级和肌层浸润深度也是重要的预后因素;两者均影响生存率。本研究与其他研究相比,提供了主要的预后因素:年龄和可手术性、肿瘤分期、组织学分级、肌层浸润深度以及盆腔和/或腹主动脉旁淋巴结受累情况。作者通过明确治疗指征得出结论。

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J Gynecol Obstet Biol Reprod (Paris). 1984;13(5):573-8.
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