Yamamoto Y, Makita K, Muramatsu K
J Nutr Sci Vitaminol (Tokyo). 1984 Jun;30(3):273-83. doi: 10.3177/jnsv.30.273.
The regulation of phenylalanine intake in rats was investigated by means of a self-selection feeding method. The relationship between phenylalanine intake and the alteration of phenylalanine and tyrosine concentrations in plasma and brain was also studied. Weanling rats were offered a choice of two diets differing only in phenylalanine content for 2 weeks. Weight gain and food consumption of all the self-selecting rats were not significantly different from each other and were of the same levels as those in rats fed on a 10% casein or 10% casein plus 1.0% phenylalanine diet as a fixed ratio. Phenylalanine intake of the self-selecting rats ranged from 0.31 to 2.29% of the food consumed. The phenylalanine and tyrosine concentrations in plasma and brain of self-selecting rats were within normal levels. It became clear that rats have an ability to regulate phenylalanine intake, and that they select phenylalanine to meet their requirement for the amino acid.
通过自选喂养方法研究了大鼠苯丙氨酸摄入量的调节情况。还研究了苯丙氨酸摄入量与血浆和脑中苯丙氨酸及酪氨酸浓度变化之间的关系。给断奶大鼠提供两种仅苯丙氨酸含量不同的日粮供其选择，持续2周。所有自选大鼠的体重增加和食物消耗量彼此无显著差异，且与以固定比例喂食10%酪蛋白或10%酪蛋白加1.0%苯丙氨酸日粮的大鼠处于相同水平。自选大鼠的苯丙氨酸摄入量占所消耗食物的0.31%至2.29%。自选大鼠血浆和脑中的苯丙氨酸及酪氨酸浓度处于正常水平。结果表明，大鼠具有调节苯丙氨酸摄入量的能力，并且它们会选择苯丙氨酸以满足其对该氨基酸的需求。
