Martini C, Fici F
Int J Clin Pharmacol Biopharm. 1978 Mar;16(3):129-31.
The clinical course of the first case of acute poisoning from melitracen, a tricyclic antidepressant, is described, whose symptomatology was characterized by the absence of cardiovascular changes (ECG, arterial pressure, cardiac frequency). Central anticholinergic effects of the drug, as excitement, hallucinations, space and time disorientation, regressed with the administration of diazepam.
描述了首例米氮平(一种三环类抗抑郁药)急性中毒的临床过程,其症状表现为无心血管变化(心电图、动脉血压、心率)。该药物的中枢抗胆碱能作用,如兴奋、幻觉、空间和时间定向障碍,在给予地西泮后消退。