Schachinger H, Frank H D, Schmid H
Monatsschr Kinderheilkd. 1984 Sep;132(9):685-8.
Bronchopulmonary dysplasia is caused by several factors. Avoidance of bronchopulmonary dysplasia is directed at its causes and should always attempt the rapid weaning of the patient from the respirator. Some of the preventive measures include a) avoiding an oxygen injury; b) prevention of barotrauma; 3) sufficient moisturization and warming of the respiratory gases; d) regular cleaning of the respiratory tract and bacterial controls of the tracheal secretion; e) administration of vitamin E; f) reconsideration (restricting the use) of parenteral nutrition. Assistance in the weaning from the respiratory means a) avoidance of an open ductus arteriosus; b) paced reduction of FiO2, respiratory pressure and frequency up to intermittent mandatory ventilation and final transition to spontaneous respiration with increased mean respiratory pressure; c) avoidance of cardiac insufficiency; d) administration of corticosteroids; e) theophyllin, and f) physical therapy. The number of patients with bronchopulmonary dysplasia has remained the same in the last six years. However, the mortality until 1979 round about 50% has been reduced to 1/3, in the years 1980/81.
支气管肺发育不良由多种因素引起。预防支气管肺发育不良需针对其病因,且应始终尝试让患者迅速脱离呼吸机。一些预防措施包括:a)避免氧损伤;b)预防气压伤;3)充分湿化和加热呼吸气体;d)定期清洁呼吸道并对气管分泌物进行细菌控制;e)给予维生素E;f)重新考虑(限制使用)肠外营养。帮助患者脱离呼吸支持的措施包括:a)避免动脉导管未闭;b)逐步降低吸入氧浓度、呼吸压力和频率,直至采用间歇强制通气,并最终过渡到平均呼吸压力增加的自主呼吸;c)避免心功能不全;d)给予皮质类固醇;e)给予茶碱;f)物理治疗。在过去六年中,支气管肺发育不良患者的数量保持不变。然而,在1980/81年,直至1979年约50%的死亡率已降至三分之一。