Protothecosis.

We have reported the 22nd case in the literature of protothecosis, a rare disease of man and animals due to infection with non-chlorophyll-producing algae of the genus Prototheca. The skin is most often affected, but generalized, disseminated involvement has been reported. Infection is usually severe and may be fatal. Amphotericin B in combination with tetracycline is the treatment of choice.