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直肠肿瘤的序贯电凝切除术

Sequential electrocoagulation and resection for carcinoma of the rectum.

作者信息

Eisenberg H W

出版信息

Surg Gynecol Obstet. 1984 Nov;159(5):471-4.

PMID:6495144
Abstract

Sequential electrocoagulation followed by resection of carcinoma of the rectum provides better survival results than have been previously obtained. More than 200 patients have been treated by this combined approach during the past ten years. The over-all five year survival rate is 67 per cent. The preferred method of treatment is sequential electrocoagulation followed by low anterior resection. When this procedure was done, 55 of the 65 patients have survived a minimum of five years. If abdominoperineal resection is necessary, the over-all survival rate is 61 per cent. The specific advantages of sequential electrocoagulation and resection are several. This procedure is safe and relatively easy to do. Electrocoagulation may be done at the time of initial biopsy as part of the preoperative evaluation. The usual interval between electrocoagulation and resection is three to five days. This may be longer in selected instances. Preoperative electrocoagulation of carcinoma of the rectum helps to prevent local recurrence on anastomoses and in the perineum. Local recurrence occurred in only 5 per cent of the patients. Electrocoagulation destroys rectal tumor cells in an area in which vascular isolation technique and wide resection of the mesentery are not possible. The efficacy of electrocoagulation in destroying tumor cells is confirmed by pathologic study of our clinical material. Combining electrocoagulation with resection may extend the limits of low anterior resection for favorable lesions allowing use of sphincter-saving procedures with less likelihood of local recurrence. Electrocoagulation, radiation therapy and surgical treatment are not mutually exclusive treatment methods. Rather, we view these modalities as complimentary in offering the potential for additive benefits.

摘要

与以往相比,直肠癌细胞的序贯电凝术继以切除术能带来更好的生存结果。在过去十年中,已有200多名患者接受了这种联合治疗方法。总体五年生存率为67%。首选的治疗方法是序贯电凝术继以低位前切除术。采用该手术时,65名患者中有55名至少存活了五年。如果有必要进行腹会阴联合切除术,总体生存率为61%。序贯电凝术和切除术具有几个特定的优点。该手术安全且相对容易实施。电凝术可在初次活检时进行,作为术前评估的一部分。电凝术与切除术之间的通常间隔为三至五天。在某些特定情况下,间隔时间可能更长。直肠癌细胞的术前电凝术有助于预防吻合口和会阴处的局部复发。仅5%的患者出现了局部复发。电凝术可在无法采用血管隔离技术和广泛切除肠系膜的区域破坏直肠肿瘤细胞。对我们临床资料的病理研究证实了电凝术在破坏肿瘤细胞方面的疗效。将电凝术与切除术相结合可扩大低位前切除术对良性病变的适用范围,从而使保肛手术的应用成为可能,且局部复发的可能性更小。电凝术、放射治疗和手术治疗并非相互排斥的治疗方法。相反,我们认为这些方式是相辅相成的,有可能带来累加的益处。

相似文献

1
Sequential electrocoagulation and resection for carcinoma of the rectum.直肠肿瘤的序贯电凝切除术
Surg Gynecol Obstet. 1984 Nov;159(5):471-4.
2
Electrocoagulation of selected carcinoma of the rectum.
Surg Gynecol Obstet. 1988 May;166(5):393-6.
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Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection.低位直肠癌根治性全直肠系膜切除术后的肿瘤学结局:前切除术与腹会阴联合切除术的比较
Dis Colon Rectum. 2004 Jan;47(1):48-58. doi: 10.1007/s10350-003-0012-y. Epub 2004 Jan 14.
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Preoperative hyperfractionated chemoradiation for locally recurrent rectal cancer in patients previously irradiated to the pelvis: A multicentric phase II study.术前超分割放化疗用于既往盆腔放疗后的局部复发性直肠癌患者:一项多中心II期研究。
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Preservation of the continence function after intersphincteric resection using a prolapsing technique in the patients with low rectal cancer and its clinical prognosis.低位直肠癌患者采用脱垂技术行括约肌间切除术后控便功能的保留及其临床预后
Chin Med J (Engl). 2008 Oct 20;121(20):2016-20.
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[Local recurrence and survival rate after rectal cancer operations and multimodal therapy].[直肠癌手术及多模式治疗后的局部复发率和生存率]
Chirurg. 2002 Mar;73(3):245-54. doi: 10.1007/s00104-002-0428-2.
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[Results of therapy of rectal cancer following anterior resection and abdominoperineal rectum amputation].[直肠癌前切除术及腹会阴直肠切除术后的治疗结果]
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[Total excision of the mesorectum in cancer of the lower and middle rectum. Oncological and functional results].[中低位直肠癌的直肠系膜全切除。肿瘤学及功能学结果]
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Abdominoperineal excision with partial anterior en bloc resection in multimodal management of low rectal cancer: a strategy to reduce local recurrence.腹会阴联合切除加局部整块前切除术在低位直肠癌多模式治疗中的应用:一种降低局部复发的策略
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Outcomes of resection of stage IV rectal cancer with mesorectal excision.经直肠系膜切除治疗IV期直肠癌的疗效
J Surg Oncol. 2006 Jun 1;93(7):523-8. doi: 10.1002/jso.20506.

引用本文的文献

1
Advanced rectal cancer.晚期直肠癌
BMJ. 1990 Feb 3;300(6720):276-7. doi: 10.1136/bmj.300.6720.276.