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直肠肿瘤的序贯电凝切除术

Sequential electrocoagulation and resection for carcinoma of the rectum.

作者信息

Eisenberg H W

出版信息

Surg Gynecol Obstet. 1984 Nov;159(5):471-4.

PMID:6495144
Abstract

Sequential electrocoagulation followed by resection of carcinoma of the rectum provides better survival results than have been previously obtained. More than 200 patients have been treated by this combined approach during the past ten years. The over-all five year survival rate is 67 per cent. The preferred method of treatment is sequential electrocoagulation followed by low anterior resection. When this procedure was done, 55 of the 65 patients have survived a minimum of five years. If abdominoperineal resection is necessary, the over-all survival rate is 61 per cent. The specific advantages of sequential electrocoagulation and resection are several. This procedure is safe and relatively easy to do. Electrocoagulation may be done at the time of initial biopsy as part of the preoperative evaluation. The usual interval between electrocoagulation and resection is three to five days. This may be longer in selected instances. Preoperative electrocoagulation of carcinoma of the rectum helps to prevent local recurrence on anastomoses and in the perineum. Local recurrence occurred in only 5 per cent of the patients. Electrocoagulation destroys rectal tumor cells in an area in which vascular isolation technique and wide resection of the mesentery are not possible. The efficacy of electrocoagulation in destroying tumor cells is confirmed by pathologic study of our clinical material. Combining electrocoagulation with resection may extend the limits of low anterior resection for favorable lesions allowing use of sphincter-saving procedures with less likelihood of local recurrence. Electrocoagulation, radiation therapy and surgical treatment are not mutually exclusive treatment methods. Rather, we view these modalities as complimentary in offering the potential for additive benefits.

摘要

与以往相比,直肠癌细胞的序贯电凝术继以切除术能带来更好的生存结果。在过去十年中,已有200多名患者接受了这种联合治疗方法。总体五年生存率为67%。首选的治疗方法是序贯电凝术继以低位前切除术。采用该手术时,65名患者中有55名至少存活了五年。如果有必要进行腹会阴联合切除术,总体生存率为61%。序贯电凝术和切除术具有几个特定的优点。该手术安全且相对容易实施。电凝术可在初次活检时进行,作为术前评估的一部分。电凝术与切除术之间的通常间隔为三至五天。在某些特定情况下,间隔时间可能更长。直肠癌细胞的术前电凝术有助于预防吻合口和会阴处的局部复发。仅5%的患者出现了局部复发。电凝术可在无法采用血管隔离技术和广泛切除肠系膜的区域破坏直肠肿瘤细胞。对我们临床资料的病理研究证实了电凝术在破坏肿瘤细胞方面的疗效。将电凝术与切除术相结合可扩大低位前切除术对良性病变的适用范围,从而使保肛手术的应用成为可能,且局部复发的可能性更小。电凝术、放射治疗和手术治疗并非相互排斥的治疗方法。相反,我们认为这些方式是相辅相成的,有可能带来累加的益处。

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