Dzhanelidze Kh N
Tsitologiia. 1984 Aug;26(8):891-5.
A-avitaminosis has been shown to provoke important ultrastructural changes in the external segments of the rods whose membrane disks disorient and disappear. No changes in the external segments of the cones were observed. The ellipsoid and paraboloid of visual cells, both rods and cones, undergo changes. The increase in the number and length of mitochondrial cristae and also the increase in the number of mitochondria themselves is noted in the ellipsoid. In the paraboloid, on the membranes of elements of endoplasmic reticulum, the number of ribosomes increase, and the number of polyribosome complexes increases in the cytoplasm. By means of the colorimetrical method, a decrease in the quantity of vitamin A is shown in the liver and retina of the sick hens. Their feedings on vitamin A provokes a restoration of the ultrastructure of membrane disks of the external segments of the rods.
已证明维生素A缺乏症会引发视杆细胞外节重要的超微结构变化,其膜盘会发生排列紊乱并消失。未观察到视锥细胞外节有变化。视杆细胞和视锥细胞这两种视觉细胞的椭球体和抛物面体会发生变化。在椭球体中,可注意到线粒体嵴的数量和长度增加,线粒体本身的数量也增加。在抛物面中,内质网元件的膜上核糖体数量增加,细胞质中多核糖体复合物的数量增加。通过比色法显示,患病母鸡的肝脏和视网膜中维生素A的含量降低。给它们喂食维生素A可促使视杆细胞外节膜盘的超微结构恢复。