针对鸡毒支原体免疫的鸡的抵抗力是由法氏囊依赖性淋巴细胞介导的。
Resistance of chickens immunized against Mycoplasma gallisepticum is mediated by bursal dependent lymphoid cells.
作者信息
Lam K M, Lin W
出版信息
Vet Microbiol. 1984 Sep;9(5):509-14. doi: 10.1016/0378-1135(84)90072-5.
PMID:6495612
Abstract
Newly hatched chickens were significantly protected against challenge by the virulent S6 strain of Mycoplasma gallisepticum after vaccination with the TS 100 mutant. Removal of the thymus did not abolish the protective effect of the vaccine, but removal of the bursa of Fabricius did. The results suggest that the resistance induced by vaccine is mediated by the bursal-dependent lymphoid cells.
摘要
用TS 100突变株疫苗接种后，新孵化的雏鸡对鸡毒支原体强毒株S6的攻击有显著的保护作用。切除胸腺并没有消除疫苗的保护作用，但切除法氏囊则消除了这种保护作用。结果表明，疫苗诱导的抗性是由依赖法氏囊的淋巴细胞介导的。
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