Haagsman H P, van Golde L M
Vet Res Commun. 1984 Aug;8(3):157-71. doi: 10.1007/BF02214708.
Triacylglycerols are the most concentrated storage form of energy for the mammalian organism. These lipids are synthesized and secreted by the liver and serve as a fuel for other tissues. This paper presents a brief review of the regulation of hepatic triacylglycerol synthesis and secretion. Particular attention will be given to the dissociation of the synthesis of triacylglycerols from that of the metabolically closely related nitrogenous phospholipids. Recent evidence is presented which suggests that triacylglycerol synthesis (and secretion) is regulated, at least partially, at the diacylglycerol branchpoint.
三酰甘油是哺乳动物机体中能量最密集的储存形式。这些脂质由肝脏合成并分泌,作为其他组织的燃料。本文简要综述了肝脏三酰甘油合成与分泌的调节。将特别关注三酰甘油合成与代谢密切相关的含氮磷脂合成的解离。文中给出了近期证据,表明三酰甘油的合成(及分泌)至少部分地在二酰甘油分支点处受到调节。