[病毒性肝炎与正常杀手]
[Viral hepatitis and normal killers].
作者信息
Farber N A, Ketiladze E S, Madzhidov A V, Rudinskiĭ V F, Fuks B B
出版信息
Vopr Virusol. 1984 Jul-Aug;29(4):431-3.
The results of the study of functional activity of normal killers in different liver diseases: acute virus hepatitis A (26 patients), acute virus hepatitis B (24 patients including 3 with hepatic coma), and 12 patients with chronic liver diseases including 8 with chronic persisting hepatitis and 4 with chronic active hepatitis are presented. A control group included 17 apparently normal subjects. The most marked decrease of the level of activity of normal killers was found in hepatic coma and in chronic active hepatitis. The expedience of determinations of the activity level of normal killers for prognosis of immediate and remote outcomes of viral hepatitides as well as for the development of new methods of immunocorrecting therapy is discussed.
不同肝脏疾病中正常杀伤细胞功能活性的研究结果如下
急性甲型病毒性肝炎（26例患者）、急性乙型病毒性肝炎（24例患者，其中3例伴有肝昏迷），以及12例慢性肝病患者，包括8例慢性持续性肝炎患者和4例慢性活动性肝炎患者。对照组包括17名表面正常的受试者。在肝昏迷和慢性活动性肝炎中发现正常杀伤细胞活性水平下降最为显著。讨论了测定正常杀伤细胞活性水平对于病毒性肝炎近期和远期预后以及开发免疫纠正治疗新方法的适用性。
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