Ferlito A, Nicolai P, Montaguti A, Cecchetto A, Pennelli N
Am J Otolaryngol. 1984 Sep-Oct;5(5):350-9. doi: 10.1016/s0196-0709(84)80005-8.
Three patients with laryngeal chondrosarcoma were observed at the ENT Department of Padua University from 1966 to 1983. Including the present observations, about 150 of these neoplasms have been described in the literature. The male to female ratio was 3:1, and the age at diagnosis ranged from 33 to 91 years (median, 66 years). The rate of metastasis was 8 per cent, and histologically positive lymph nodes developed in only five patients. Surgery is the treatment of choice for laryngeal chondrosarcoma. Radical neck dissection does not appear to be indicated, unless results of clinical examination suggest metastatic lymph nodal involvement.
1966年至1983年期间,帕多瓦大学耳鼻喉科观察到3例喉软骨肉瘤患者。包括本次观察在内,文献中已描述了约150例此类肿瘤。男女比例为3:1,诊断时年龄范围为33至91岁(中位数为66岁)。转移率为8%,仅5例患者出现组织学阳性淋巴结。手术是喉软骨肉瘤的首选治疗方法。除非临床检查结果提示有转移性淋巴结受累,否则似乎无需进行根治性颈清扫术。