胎儿抗惊厥综合征中的功能性腭功能不全。
Functional palatal incompetence in the fetal anticonvulsant syndrome.
作者信息
Pearl K N, Dickens S, Latham P
出版信息
Arch Dis Child. 1984 Oct;59(10):989-90. doi: 10.1136/adc.59.10.989.
Abstract
We report two children with mild mental retardation and appreciable articulation difficulties whose mothers took phenobarbitone and phenytoin throughout their pregnancies. The speech difficulties in both children were due to malfunction of an anatomically normal palate.
摘要
我们报告了两名患有轻度智力迟钝且有明显发音困难的儿童，他们的母亲在整个孕期都服用了苯巴比妥和苯妥英。两名儿童的言语困难均是由于解剖结构正常的腭部功能异常所致。
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本文引用的文献
1
The teratogenicity of epilepsy.癫痫的致畸性。
Dev Med Child Neurol. 1974 Jun;16(3):375-6. doi: 10.1111/j.1469-8749.1974.tb03352.x.
2
Anticonvulsant drugs and congenital abnormalities.抗惊厥药物与先天性异常。
Lancet. 1968 Dec 14;2(7581):1296. doi: 10.1016/s0140-6736(68)91781-9.
3
Studies of the development of congenital anomalies in rats. III. Effects of inhibition of mitochondrial energy systems on embryonic development.大鼠先天性异常发育的研究。III. 线粒体能量系统抑制对胚胎发育的影响。
Teratology. 1975 Dec;12(3):291-6. doi: 10.1002/tera.1420120311.
4
Comparative study of the teratogenicity of phenobarbitone, diphenylhydantoin and carbamazepine in mice.苯巴比妥、苯妥英钠和卡马西平对小鼠致畸性的比较研究。
Toxicology. 1976 Nov-Dec;6(3):323-30. doi: 10.1016/0300-483x(76)90036-6.
5
Growth retardation, dysmorphic facies and minor malformations following massive exposure to phenobarbitone in utero.
Acta Paediatr Scand. 1976 Sep;65(5):617-21. doi: 10.1111/j.1651-2227.1976.tb04941.x.
6
The fetal hydantoin syndrome.胎儿苯妥英钠综合征
J Pediatr. 1975 Aug;87(2):285-90. doi: 10.1016/s0022-3476(75)80604-4.
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