Giler S, Henig E F, Urca I, Sperling O, de Vries A
J Clin Pathol. 1978 May;31(5):444-6. doi: 10.1136/jcp.31.5.444.
Xanthine oxidase (XO) activity was found to be negligible in sterile human urines (less than 480 units, as presently defined, per litre). Significant XO activity was found in all urines containing more than 10(5) bacteria/ml, except for urines infected with Staphylococcus aureus, in which XO activity ranged from 347 to 714 units per litre. Plasma XO is not transferred to the urine, as demonstrated by the negligible XO activity found in sterile urines from patients with raised plasma XO activity. Determination of urinary XO activity is a suitable procedure for the detection of urinary tract infection.
在无菌人尿中发现黄嘌呤氧化酶（XO）活性可忽略不计（每升低于目前定义的480单位）。在所有每毫升含有超过10⁵细菌的尿液中均发现有显著的XO活性，但感染金黄色葡萄球菌的尿液除外，其XO活性范围为每升347至714单位。血浆中的XO不会转移至尿液，这一点可通过血浆XO活性升高患者的无菌尿液中XO活性可忽略不计得到证明。测定尿中XO活性是检测尿路感染的合适方法。
