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[摄入不均衡蛋白质对生长中大鼠肝脏的影响]

[Effect of the intake of imbalanced protein on the liver of growing rats].

作者信息

Tirapegui J O, De Angelis R C

出版信息

Arq Gastroenterol. 1984 Jan-Mar;21(1):29-34.

PMID:6497706
Abstract

The goal of the present work was to reproduce in laboratory animals situations frequently observed in low-income population, such as the insufficient energetic ingestion associated with protein sources of inferior quality. Corn was chosen as the protein source of low biological value and casein as the reference protein. The latter was administered in adequate quantity (20%) or equal to that of the corn (10%). Several biochemical parameters and the amounts of DNA, RNA and protein in the liver of rats in a phase of rapid growth were studied. In result, we can attest that the group fed on corn were the most seriously compromised in body weight, liver weight and biochemical parameters with the group fed a restricted diet of corn being the most seriously affected. The results suggest that the alterations caused by ingestion of a balanced diet restricted in quantity were less accentuated that those observed when the diet was of corn "ad libitum".

摘要

本研究的目的是在实验动物中重现低收入人群中经常观察到的情况,例如与低质量蛋白质来源相关的能量摄入不足。选择玉米作为生物价值低的蛋白质来源,酪蛋白作为参考蛋白质。后者以适量(20%)或与玉米等量(10%)给予。研究了快速生长阶段大鼠肝脏中的几种生化参数以及DNA、RNA和蛋白质的含量。结果表明,以玉米为食的组在体重、肝脏重量和生化参数方面受到的影响最大,其中以限量玉米饮食喂养的组受影响最为严重。结果表明,摄入限量均衡饮食所引起的变化不如随意摄入玉米饮食时观察到的变化那么明显。

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