De Assis J L, Scaff M, Zambon A A, Marchiori P E
Arq Neuropsiquiatr. 1984 Sep;42(3):226-31. doi: 10.1590/s0004-282x1984000300006.
In a group of 304 myasthenic patients 15 cases with thyropathies were reported: nine with hyperthyroidism, one with hypothyroidism and five with nontoxic goiter. Four patients presented diffuse simple goiter and one a multinodular goiter with normal thyroid function. No patient came from an endemic goiter region, not even familial goiter. The prevalence and influence of hyperthyroidism on myasthenic symptomatology were studied. Our findings suggest that there is no clinical correlation between both myasthenia symptomatology and thyroid dysfunction, neither significant influence on myasthenic symptoms when the endocrine disorders improve.
在一组304例肌无力患者中,报告了15例甲状腺疾病患者:9例甲状腺功能亢进,1例甲状腺功能减退,5例非毒性甲状腺肿。4例患者表现为弥漫性单纯性甲状腺肿,1例为甲状腺功能正常的结节性甲状腺肿。没有患者来自地方性甲状腺肿地区,甚至没有家族性甲状腺肿患者。研究了甲状腺功能亢进对肌无力症状学的患病率和影响。我们的研究结果表明,肌无力症状学与甲状腺功能障碍之间没有临床相关性,内分泌紊乱改善时对肌无力症状也没有显著影响。