Maeda Y, Hayashi K, Toyohara S, Hashiguchi T
Biochem Genet. 1984 Aug;22(7-8):687-700. doi: 10.1007/BF00485853.
Fractional rates (% X day-1) of synthesis and degradation were determined by measuring the output of N tau-methylhistidine (MeHis) in the excreta at 4 and 8 weeks of age in the chicken. At 4 weeks of age, the fractional rate of synthesis of the meat-type stock was twice that of the egg-type stock (White Leghorn), but the fractional rates of synthesis at 8 weeks of age were similar (4.1-5.1% X day-1) among stocks. The fractional rate of degradation (1.3-1.5% X day-1) of the meat-type stock at 8 weeks of age was less than half the rate of the egg-type stock (2.9% X day-1). The fractional rates of synthesis and degradation at 4 weeks of age in the Satsuma native fowl were relatively high compared with those in the other stocks. In particular, the rate of degradation (8.6% X day-1) at 4 weeks of age was approximately twice that of other stocks. These results show that fractional rates of synthesis and degradation of muscle protein in the chicken differ among genetically diverse groups. The effect of changes in rates of synthesis and degradation on the change in fractional growth rate also differed. From regression coefficients (bks . FGR and bKd . FGR) of these rates in skeletal muscle protein on the fractional growth rate, it was recognized that the change in growth rate accompanies the changes in both synthesis and degradation in White Leghorn and commercial broilers but only the change in synthesis in White Plymouth Rock (dw) and Satsuma native fowl.
通过测量鸡在4周龄和8周龄时排泄物中N-τ-甲基组氨酸（MeHis）的排出量，测定了合成和降解的分数速率（%×天⁻¹）。在4周龄时，肉用型鸡的合成分数速率是蛋用型鸡（白来航鸡）的两倍，但在8周龄时，各品种间的合成分数速率相似（4.1 - 5.1%×天⁻¹）。8周龄时肉用型鸡的降解分数速率（1.3 - 1.5%×天⁻¹）不到蛋用型鸡（2.9%×天⁻¹）的一半。与其他品种相比，萨摩土鸡在4周龄时的合成和降解分数速率相对较高。特别是，4周龄时的降解速率（8.6%×天⁻¹）约为其他品种的两倍。这些结果表明，鸡肌肉蛋白的合成和降解分数速率在遗传背景不同的群体中存在差异。合成和降解速率变化对分数生长速率变化的影响也不同。从骨骼肌蛋白中这些速率与分数生长速率的回归系数（bks.FGR和bKd.FGR）可以看出，白来航鸡和商品肉鸡的生长速率变化伴随着合成和降解的变化，而白普利茅斯洛克鸡（dw）和萨摩土鸡只伴随着合成的变化。
