Donatelli M, Bucalo M L, Russo V, Cerasola G A
Boll Soc Ital Biol Sper. 1984 Aug 31;60(8):1503-8.
To evaluate calcium hormones in diabetic pregnancy, eleven diabetic pregnant women were studied by measuring serum total calcium, phosphorus by conventional methods, and parathyroid hormone, calcitonin and 25-hydroxycholecalciferol, by radioimmunologic methods, serially every four weeks, beginning at 16th week throughout 36th week of gestation. Serum total calcium, phosphorus and parathyroid hormone levels dit not differ between diabetic and non diabetic pregnant women, nor between all pregnant women and age-matched non pregnant healthy women. Serum calcitonin levels, although significantly higher than those of age-matched non pregnant women, did not differ between diabetic and non diabetic pregnant women, maintaining constant with the progression of pregnancy. Serum 25-hydroxycholecalciferol levels, although contained within the normal range, increased significantly in the third trimester of gestation both in non diabetic pregnant women and, even though later, in diabetic pregnant women.
为评估糖尿病孕妇体内的钙调节激素，对11名糖尿病孕妇进行了研究。从妊娠第16周开始至第36周，每四周对其进行一次连续检测，采用传统方法测定血清总钙、磷水平，采用放射免疫法测定甲状旁腺激素、降钙素及25-羟胆钙化醇水平。糖尿病孕妇与非糖尿病孕妇之间，以及所有孕妇与年龄匹配的非孕健康女性之间，血清总钙、磷及甲状旁腺激素水平均无差异。血清降钙素水平虽显著高于年龄匹配的非孕女性，但糖尿病孕妇与非糖尿病孕妇之间并无差异，且随妊娠进展保持恒定。血清25-羟胆钙化醇水平虽在正常范围内，但在非糖尿病孕妇妊娠晚期显著升高，糖尿病孕妇虽稍晚，但也出现了类似升高。
