Kotliar B I, Miasnikov A A, Kartaev S D, Norekian T P, Medvedovskiĭ B V
Nauchnye Doki Vyss Shkoly Biol Nauki. 1984(9):52-6.
The absence of habituation effect to the iontophoretic repetitive applications with 120, 30 and 15 seconds intervals of inhibition transmitter--gamma aminobutiric acid (GABA)--in sensomotor cortex neurons has been established. Earlier habituation effect has been discovered under the same experimental conditions during other transmitter administration--acetilcholine. A hypothesis concerning the absence of biological expendiency of habituation in the GABA-ergic system is suggested.
已证实,在感觉运动皮层神经元中,对间隔120秒、30秒和15秒进行离子电渗重复应用抑制性递质——γ-氨基丁酸(GABA)时不存在习惯化效应。早期在相同实验条件下给予其他递质——乙酰胆碱时发现了习惯化效应。提出了一个关于GABA能系统中习惯化缺乏生物学适应性的假说。