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胎儿肌肉创伤的子宫内愈合:大鼠实验研究

The intra-uterine healing of foetal muscle wounds: experimental study in the rat.

作者信息

Rowsell A R

出版信息

Br J Plast Surg. 1984 Oct;37(4):635-42. doi: 10.1016/0007-1226(84)90166-8.

DOI:10.1016/0007-1226(84)90166-8
PMID:6498408
Abstract

This work confirms that foetal wound healing is rapid, occurs without an apparent inflammatory response and takes place without the deposition of collagen. It is shown for the first time that foetal muscle wounds heal by regeneration. This study also shows that, immediately after injury, there is a degeneration of mesenchymal and ectodermal elements in that part of the lip between the wound and the mid line. This degeneration is followed by regeneration of only the mesenchymal elements.

摘要

这项研究证实,胎儿伤口愈合迅速,在没有明显炎症反应的情况下发生,且无需胶原蛋白沉积。首次表明胎儿肌肉伤口通过再生愈合。该研究还表明,受伤后立即出现伤口与中线之间唇部区域的间充质和外胚层成分退化。这种退化之后仅间充质成分再生。

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The intra-uterine healing of foetal muscle wounds: experimental study in the rat.胎儿肌肉创伤的子宫内愈合:大鼠实验研究
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引用本文的文献

1
Collagen content of uninjured skin and scar tissue in foetal and adult sheep.胎儿和成年绵羊未受伤皮肤及瘢痕组织的胶原蛋白含量
Int J Exp Pathol. 1993 Dec;74(6):583-91.
2
Studies in fetal wound healing. IV. Hyaluronic acid-stimulating activity distinguishes fetal wound fluid from adult wound fluid.胎儿伤口愈合的研究。IV. 透明质酸刺激活性使胎儿伤口液与成人伤口液相区分。
Ann Surg. 1989 Nov;210(5):667-72. doi: 10.1097/00000658-198911000-00016.
3
Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid.
胎儿伤口愈合的研究。V. 透明质酸的长期存在是胎儿伤口液的特征。
Ann Surg. 1991 Apr;213(4):292-6. doi: 10.1097/00000658-199104000-00003.
4
Extracellular matrix contraction by fibroblasts: peptide promoters and second messengers.成纤维细胞介导的细胞外基质收缩:肽启动子和第二信使
Cancer Metastasis Rev. 1992 Mar;11(1):45-54. doi: 10.1007/BF00047602.