Cunningham M, de Torrenté A, Ekoé J M, Ackermann J P, Humair L
Br J Surg. 1984 Nov;71(11):829-31. doi: 10.1002/bjs.1800711106.
A case is reported of a multiple trauma victim who developed severe vascular spasm whilst receiving heparin-dihydro-ergotamine thromboembolic prophylaxis which ultimately led to amputation of the right foot. Identification of high risk groups for this complication is attempted from a review of the literature. Treatment should be with intra-arterial or intravenous nitroprusside or nitrates. Little information is as yet available on the use of prostacyclin in this condition.
报道了一例多发伤患者，在接受肝素 - 双氢麦角胺预防血栓栓塞治疗时发生严重血管痉挛，最终导致右脚截肢。通过文献回顾试图确定该并发症的高危人群。治疗应采用动脉内或静脉内硝普钠或硝酸盐。关于在这种情况下使用前列环素的信息目前还很少。
