Greenfield L J, Langham M R
Br J Surg. 1984 Dec;71(12):968-70. doi: 10.1002/bjs.1800711220.
Management of angiographically confirmed pulmonary thromboembolism in 313 patients has been based on a physiological classification system. Patients in shock (Class IV) are managed either by catheter embolectomy (26 patients) with 27 per cent mortality rate or by open embolectomy during active resuscitation (6 patients) with a 33 per cent mortality rate. High-risk patients with transient hypotension (Class III) are managed by anticoagulation and filter insertion. The most common indication for filter placement is a contra-indication to anticoagulation (37 per cent). Filter placement was infrarenal in 268 patients (86 per cent) and intentionally suprarenal in 19 patients (6 per cent). Misplacement has occurred into the iliac veins, renal veins and the heart but has not been seen since the guide wire technique for insertion was developed. The 30 day mortality for patients receiving filters was 14 per cent and due to other disorders. Only one death was suspected from recurrent embolism. One hundred and thirteen venacavagrams at intervals up to 99 months in 110 patients showed long-term patency in 97 per cent. Recurrent embolism was seen in five patients (2 per cent) but caused no deaths.
对313例经血管造影证实的肺血栓栓塞患者的治疗是基于一种生理学分类系统。休克患者(IV级)采用导管取栓术(26例)治疗,死亡率为27%;或在积极复苏期间进行开放取栓术(6例),死亡率为33%。伴有短暂低血压的高危患者(III级)采用抗凝和置入滤器治疗。滤器置入最常见的指征是抗凝禁忌(37%)。268例患者(86%)的滤器置入位置在肾下,19例患者(6%)有意置于肾上。曾发生过滤器误置入髂静脉、肾静脉和心脏的情况,但自从采用导丝置入技术后就未再出现过。接受滤器治疗患者的30天死亡率为14%,死亡原因是其他疾病。仅1例死亡怀疑是复发性栓塞所致。110例患者间隔最长99个月进行了113次腔静脉造影,结果显示97%的患者长期通畅。5例患者(2%)出现复发性栓塞,但均未导致死亡。