Bayorh M A, Zukowska-Grojec Z, Palkovits M, Kopin I J
Brain Res. 1984 Nov 12;321(2):315-8. doi: 10.1016/0006-8993(84)90184-7.
PCP (10 mg/kg, s.c.) causes hypertension that is associated with decrease or tendency to decrease the levels of epinephrine and norepinephrine in the hypothalamus and the brainstem regions. If this represents a decreased catecholaminergic activity, then this may enhance sympathetic activity and contribute to the PCP-induced hypertension.
苯环己哌啶(10毫克/千克,皮下注射)会引发高血压,这与下丘脑和脑干区域中肾上腺素和去甲肾上腺素水平的降低或降低趋势有关。如果这代表儿茶酚胺能活性降低,那么这可能会增强交感神经活动并导致苯环己哌啶诱发的高血压。