Sakaguchi T, Shirokawa T, Nakamura S
Brain Res. 1984 Nov 12;321(2):319-22. doi: 10.1016/0006-8993(84)90185-9.
The visual cortex of adult rats was unilaterally ablated. A histofluorescence study revealed an increase of noradrenergic terminals in the lateral geniculate nucleus (LGN) ipsilateral to the decortication, confirming the previous report. Corresponding to this, the frequency for encountering neurons in the locus coeruleus (LC) activated antidromically from the LGN was increased. We suggest that LC neurons whose axon terminals were damaged by ablation of the visual cortex formed new axons or axon collaterals (pruning effect) in the LGN, thus contributing, at least partly, to the increase of noradrenergic terminals therein.
成年大鼠的视觉皮层被单侧切除。一项组织荧光研究显示，去皮质对侧的外侧膝状体核（LGN）中去甲肾上腺素能终末增加，这证实了先前的报道。与此相应，从LGN逆向激活的蓝斑（LC）中遇到的神经元频率增加。我们认为，其轴突终末因视觉皮层切除而受损的LC神经元在LGN中形成了新的轴突或轴突侧支（修剪效应），从而至少部分地导致了其中去甲肾上腺素能终末的增加。
