Jordan D R, Drouin J, Berry G, Watson A G
Can J Ophthalmol. 1984 Oct;19(6):275-8.
A 58-year-old man with multiple myeloma presented with a 3-month history of a sensation of occipital pressure, transient blurring of vision and increased bone pain. Funduscopic examination revealed disc swelling, tortuous veins and superficial retinal hemorrhages simulating early hyperviscosity syndrome. Clinical investigation and computerized tomography, however, indicated that an intracranial plasmacytoma was the cause of his papilledema. Cobalt 60 beam therapy and vincristine were added to his treatment regimen. Seven weeks later the intracranial tumour had almost totally disappeared. Symptomatic cerebral compression from an intracranial plasmacytoma associated with systemic disease is uncommon. The diagnosis and management are reviewed.
一名58岁的多发性骨髓瘤男性患者,出现枕部压迫感、短暂视力模糊和骨痛加重3个月。眼底检查发现视盘肿胀、静脉迂曲和视网膜浅层出血,类似早期高黏滞综合征。然而,临床检查和计算机断层扫描表明,颅内浆细胞瘤是其视乳头水肿的病因。其治疗方案中加入了钴60射线治疗和长春新碱。7周后,颅内肿瘤几乎完全消失。与全身性疾病相关的颅内浆细胞瘤引起的症状性脑压迫并不常见。本文对其诊断和治疗进行了综述。