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[乙基亚硝基脲诱导的神经系统肿瘤细胞核中的DNA水平]

[DNA levels in the cell nuclei of nervous system tumors induced by ethylnitrosourea].

作者信息

Khalanskiĭ A S, Iablonovskaia L Ia, Kondakova L I, Morozov Iu E

出版信息

Eksp Onkol. 1984;6(1):32-6.

PMID:6499729
Abstract

Distribution of DNA in cells of 28 primary ethylnitrosourea-induced tumours of the rat nervous system was studied by the Feulgen cytophotometry method. Out of them 20 had paradiploid DNA quantity, 3 tumours--hypodiploid and 4--hyperdiploid content of DNA. A high heterogeneity of the DNA quantity and the absence of expressed modal class were found only in one case. No correlation is found between the DNA distribution in gliomas and the stage of their malignancy.

摘要

采用福尔根细胞光度法研究了28例原发性大鼠神经系统乙基亚硝基脲诱发肿瘤细胞中的DNA分布。其中20例肿瘤细胞的DNA含量为亚二倍体,3例为次二倍体,4例为超二倍体。仅在1例中发现DNA含量高度异质性且无明显的众数类。未发现胶质瘤中的DNA分布与其恶性程度之间存在相关性。

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