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First clinical observations with hPTH(1-38), a more potent human parathyroid hormone peptide.

作者信息

Hesch R D, Heck J, Auf'mKolk B, Schettler T, Atkinson M J

出版信息

Horm Metab Res. 1984 Oct;16(10):559-60. doi: 10.1055/s-2007-1014852.

DOI:10.1055/s-2007-1014852
PMID:6500494
Abstract
摘要

相似文献

1
First clinical observations with hPTH(1-38), a more potent human parathyroid hormone peptide.首次使用更具活性的人甲状旁腺激素肽hPTH(1-38)进行的临床观察。
Horm Metab Res. 1984 Oct;16(10):559-60. doi: 10.1055/s-2007-1014852.
2
The effect of age on bone and renal responsiveness to parathyroid hormone infusion in man.年龄对人体骨骼及肾脏对甲状旁腺激素输注反应性的影响。
J Endocrinol Invest. 1992;15(9 Suppl 6):69-72.
3
Full length or fragments in hormone studies?
J Bone Miner Res. 2006 May;21(5):801; author reply 802. doi: 10.1359/jbmr.060211.
4
Intermittent Fugu parathyroid hormone 1 (1-34) is an anabolic bone agent in young male rats and osteopenic ovariectomized rats.间歇性给予的河豚甲状旁腺激素1-34对年轻雄性大鼠和去卵巢骨质疏松大鼠是一种促合成代谢的骨药物。
Bone. 2008 Jun;42(6):1164-74. doi: 10.1016/j.bone.2008.01.015. Epub 2008 Feb 13.
5
Expression-level dependent activation of recombinant human parathyroid hormone/parathyroid hormone-related peptide receptor: effect of human parathyroid hormone (1-34), (1-31), and (28-48).
J Recept Signal Transduct Res. 2000 May-Aug;20(2-3):133-51. doi: 10.3109/10799890009150641.
6
Human PTH-(3-34) inhibited the effects of human parathyroid hormone-related protein on phosphate uptake in a cultured renal cell line (OK cells).人甲状旁腺激素(3-34)抑制人甲状旁腺激素相关蛋白对培养的肾细胞系(OK细胞)中磷酸盐摄取的作用。
J Bone Miner Res. 1990 Oct;5(10):995-1002. doi: 10.1002/jbmr.5650051002.
7
Stimulation of protein kinase C activity in cells expressing human parathyroid hormone receptors by C- and N-terminally truncated fragments of parathyroid hormone 1-34.甲状旁腺激素1-34的C端和N端截短片段对表达人甲状旁腺激素受体的细胞中蛋白激酶C活性的刺激作用。
J Bone Miner Res. 2001 Mar;16(3):441-7. doi: 10.1359/jbmr.2001.16.3.441.
8
Both hPTH(1-34) and bFGF increase trabecular bone mass in osteopenic rats but they have different effects on trabecular bone architecture.人甲状旁腺激素(1-34)[hPTH(1-34)]和碱性成纤维细胞生长因子(bFGF)均可增加骨质减少大鼠的小梁骨量,但它们对小梁骨结构有不同影响。
J Bone Miner Res. 2003 Dec;18(12):2105-15. doi: 10.1359/jbmr.2003.18.12.2105.
9
The action of parathyroid hormone on bone metabolism may be regulated by endogenously synthesized prostaglandin E2.
Adv Prostaglandin Thromboxane Leukot Res. 1989;19:435-8.
10
Cyclic AMP formation in rat bone and kidney cells is stimulated equally by parathyroid hormone-related protein (PTHrP) 1-34 and PTH 1-34.甲状旁腺激素相关蛋白(PTHrP)1-34和甲状旁腺激素(PTH)1-34对大鼠骨细胞和肾细胞中环磷酸腺苷(cAMP)形成的刺激作用相同。
Exp Clin Endocrinol. 1993;101(3):150-5. doi: 10.1055/s-0029-1211222.

引用本文的文献

1
Increase of vertebral density by combination therapy with pulsatile 1-38hPTH and sequential addition of calcitonin nasal spray in osteoporotic patients.在骨质疏松症患者中,采用脉冲式1-38hPTH联合治疗并序贯添加降钙素鼻喷雾剂增加椎体密度。
Calcif Tissue Int. 1989 Mar;44(3):176-80. doi: 10.1007/BF02556561.