Upton J D
Horm Metab Res. 1984 Jun;16(6):290-2. doi: 10.1055/s-2007-1014771.
Intravenous glucose tolerance tests (I.V.G.T.T.) were carried out in fasting NZO, NZB and NZB/W mice. NZO and NZB mice exhibited an impaired rate of glucose decay, while NZB/W mice cleared glucose very rapidly. The possibility that autoimmune processes are responsible for the glucose intolerance observed in NZO and NZB mice is discussed.
对禁食的新西兰肥胖(NZO)小鼠、新西兰黑(NZB)小鼠和新西兰黑/白(NZB/W)小鼠进行了静脉葡萄糖耐量试验(I.V.G.T.T.)。NZO和NZB小鼠的葡萄糖衰减速率受损,而NZB/W小鼠清除葡萄糖的速度非常快。本文讨论了自身免疫过程是否是NZO和NZB小鼠中观察到的葡萄糖不耐受的原因。