Horiuchi S, Ono S
Int J Vitam Nutr Res. 1984;54(2-3):173-7.
This study was undertaken to investigate the effects of riboflavin administration on the phospholipid metabolism of rat liver impaired with carbon tetrachloride. Although the specific radioactivity in the CCl4 group decreased, the groups pretreated with riboflavin, especially B2-butyrate group, were prevented a decrease of 32P incorporation into total phospholipid in liver. The percentage of 32P incorporation into phosphatidylcholine in both mitochondria and microsomes was increased by the administration of riboflavin.
本研究旨在探讨给予核黄素对四氯化碳损伤的大鼠肝脏磷脂代谢的影响。虽然四氯化碳组的比放射性降低，但预先用核黄素处理的组，尤其是B2-丁酸盐组，可防止肝脏中总磷脂的32P掺入量减少。给予核黄素可增加线粒体和微粒体中32P掺入磷脂酰胆碱的百分比。
