Marcus D C, Kobayashi T, Rokugo M, Marcus N Y, Thalmann I, Thalmann R
Hear Res. 1984 Sep;15(3):287-92. doi: 10.1016/0378-5955(84)90035-2.
Morphologic considerations would seem to suggest that the cochlear duct could not be maintained in a fully functional state in the absence of a blood supply. We found, however, that perilymphatic perfusion could be used as a substitute for the normal vascular circulation. The criteria used to determine cochlear function included (1) normal endocochlear potential, (2) normal net secretory flux of rubidium (as a tracer for K), and (3) normal levels of ATP in both the organ of Corti and the stria vascularis. All criteria were satisfied by our perfusion regimen.
形态学方面的考虑似乎表明，在没有血液供应的情况下，蜗管无法维持在完全功能状态。然而，我们发现外淋巴灌注可以替代正常的血管循环。用于确定耳蜗功能的标准包括：（1）正常的内淋巴电位；（2）正常的铷净分泌通量（作为钾的示踪剂）；以及（3）柯蒂器和血管纹中三磷酸腺苷（ATP）的正常水平。我们的灌注方案满足了所有这些标准。
