The in-vitro susceptibility of the Bacteroides fragilis group to amoxycillin-clavulanic acid.

The susceptibility to amoxycillin-clavulanic acid of 150 strains belonging to the Bacteroides fragilis group was tested by both disc diffusion and agar dilution methods. On the basis of minimum inhibitory concentrations (MICs), at least 99% of the isolates were sensitive to this agent. However, problems encountered with the disc diffusion method suggest that at present it is unsatisfactory for assessing the in-vitro activity of amoxycillin-clavulanic acid against this group of organisms.