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川崎病:26例患者的报告。

Kawasaki disease: a report of 26 patients.

作者信息

Gray J A, Welsby P D

出版信息

J Infect. 1984 Jul;9(1):17-21. doi: 10.1016/s0163-4453(84)94394-9.

DOI:10.1016/s0163-4453(84)94394-9
PMID:6501894
Abstract

Twenty-six patients suffering from Kawasaki Disease (24 from the U.K. and two from the Netherlands) were reported and their details documented on a questionnaire returned by members of the British Society for the Study of Infection between 1981 and 1983. Seventeen of the children (65.4%) were presumed British extraction. The male:female ratio was 1.6:1.0 and their mean age 3.38 years. No seasonal variation was noted. The clinical and laboratory findings are detailed. Little evidence of infection was discovered. Two patients, both British, died of myocardial infarction (7.7%). Four of the 24 survivors had evidence of coronary artery abnormalities making a total of six (23.1%) of the total series of 26 patients to have coronary artery disease demonstrated. Of the three patients (11.5%) given corticosteroids, two died. The significance of these findings is briefly discussed.

摘要

报告了26例川崎病患者(24例来自英国,2例来自荷兰),其详细信息记录在英国感染研究学会成员于1981年至1983年返回的一份问卷上。其中17名儿童(65.4%)推测有英国血统。男女比例为1.6:1.0,平均年龄3.38岁。未发现季节性差异。详细列出了临床和实验室检查结果。几乎没有发现感染迹象。两名英国患者死于心肌梗死(7.7%)。24名幸存者中有4人有冠状动脉异常的证据,在26例患者的总系列中共有6人(23.1%)被证实患有冠状动脉疾病。在接受皮质类固醇治疗的3例患者(11.5%)中,2例死亡。简要讨论了这些发现的意义。

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