Norman R W, Bath S S, Robertson W G, Peacock M
J Urol. 1984 Dec;132(6):1137-9. doi: 10.1016/s0022-5347(17)50064-6.
To determine the optimal time at which to assess the urinary risk factors for calcium stone formation, we followed 11 patients after an episode of acute renal colic with sequential 24-hour urine collections, first in the hospital and then at regular intervals after they were discharged from the hospital. The changes that occurred in the urinary risk factors were compared to those of a control group in which samples were collected during the same interval. The in-hospital 24-hour urine volumes were high but decreased gradually to approach the relatively constant volume of the control group by 3 months. The opposite trend occurred with respect to the 24-hour urinary excretion of calcium. There were no significant changes in the 24-hour urinary pH or excretions of oxalate, uric acid and alcian blue precipitable polyanions. The over-all effect was to cause a progressive increase in the probability of stones forming in the patients. The accurate assessment of the urinary risk factors of calcium stone disease requires at least a 3-month delay following acute renal colic. This delay usually will provide sufficient time for the stone to pass and for the patient to return to the normal dietary and fluid intake.
为了确定评估钙结石形成的尿液危险因素的最佳时间，我们对11例急性肾绞痛发作后的患者进行了随访，依次收集24小时尿液，先是在医院内，然后在他们出院后定期收集。将尿液危险因素发生的变化与在相同时间段收集样本的对照组的变化进行比较。住院期间24小时尿量较高，但逐渐减少，到3个月时接近对照组相对稳定的尿量。钙的24小时尿排泄量则呈现相反的趋势。24小时尿pH值以及草酸盐、尿酸和阿利新蓝可沉淀多阴离子的排泄量没有显著变化。总体效果是导致患者形成结石的可能性逐渐增加。准确评估钙结石病的尿液危险因素需要在急性肾绞痛后至少延迟3个月。这段延迟通常将为结石排出以及患者恢复正常饮食和液体摄入量提供足够的时间。
