Ando K
Gan No Rinsho. 1984 Sep;30(11):1398-400.
We examined whether fast-neutron radiotherapy is superior to low-LET radiotherapy by comparing the relationship between cell survival and tumor control probabilities after exposure of tumor-bearing (species) to the two modalities. Analysis based on TCD50 assay and lung colony assay indicated that single dose of fast neutron achieved animal cures at higher survival rates than other radiation modalities including single and fractionated gamma-ray doses, fractionated doses of fast neutron, and the mixed-beam scheme with a sequence of N-gamma-gamma-gamma-N. We conclude that fast-neutron radiotherapy cured animal tumors with lower cell killing rates other radiation modalities.
我们通过比较荷瘤（物种）接受这两种放疗方式后细胞存活与肿瘤控制概率之间的关系，来研究快中子放疗是否优于低传能线密度放疗。基于TCD50测定法和肺集落测定法的分析表明，单剂量快中子实现动物治愈的存活率高于其他放疗方式，包括单次和分次γ射线剂量、分次快中子剂量以及N-γ-γ-γ-N序列的混合束方案。我们得出结论，快中子放疗治愈动物肿瘤时的细胞杀伤率低于其他放疗方式。
