Lineaweaver W C, Brunson M B, Smith J F, Franzini D A, Rumley T O
J Surg Oncol. 1984 Dec;27(4):239-42. doi: 10.1002/jso.2930270409.
A patient with squamous cell carcinoma arising from an extensive pilonidal sinus was treated with wide local excision, resulting in an apparent cure over a 1-year follow-up period. Review of the literature revealed 32 previously reported cases of this entity. Forty-four percent of these patients developed recurrences or metastases, and 22% died of their disease. The largest historical treatment group with at least 1-year follow-up (19 patients with localized disease) underwent wide excision. Forty-two percent of these patients recurred or developed metastases. Ultimately, 89.5% of these patients were reported cured, but only five survivors were followed for as long as 5 years. Historical experience appears to identify pilonidal tract squamous carcinoma as an aggressive tumor. The reported success of wide local excision is based on a small number of patients followed for short periods of time. Continued experience with this disease should be reported to verify the adequacy of local excision or identify the need for adjunctive therapy.
一名患有源于广泛藏毛窦的鳞状细胞癌患者接受了广泛局部切除治疗，在1年的随访期内实现了明显治愈。文献回顾显示，此前已有32例该实体病例的报道。这些患者中有44%出现复发或转移，22%死于该疾病。历史上最大的至少有1年随访的治疗组（19例局限性疾病患者）接受了广泛切除。这些患者中有42%复发或出现转移。最终，据报道这些患者中有89.5%被治愈，但只有5名幸存者的随访时间长达5年。历史经验似乎表明藏毛窦道鳞状癌是一种侵袭性肿瘤。所报道的广泛局部切除的成功是基于少数患者的短期随访。应报告对该疾病的持续经验，以验证局部切除的充分性或确定辅助治疗的必要性。
