Feldman B F, Ruehl W W
Mod Vet Pract. 1984 Oct;65(10):771-3.
Hematologic alterations unrelated to neoplastic bone marrow involvement include polycythemia, anemia, leukocytosis, leukopenia, thrombocytosis, thrombocytopenia and coagulopathies. Serum globulin levels may be increased or decreased, depending on the type of neoplasm. Plasma fibrinogen and fibrin degradation product concentrations are usually elevated in cancer patients, whereas cancer patients with DIC have low plasma fibrinogen concentrations. Hypercalcemia can be a sequel of osseous metastases. Neoplasia may cause the nephrotic syndrome in some patients. Effusions should be examined microscopically for signs of malignancy. Elevated serum enzyme levels are not specific in neoplastic disease.
与肿瘤性骨髓受累无关的血液学改变包括红细胞增多症、贫血、白细胞增多、白细胞减少、血小板增多、血小板减少和凝血病。血清球蛋白水平可能升高或降低，这取决于肿瘤的类型。癌症患者血浆纤维蛋白原和纤维蛋白降解产物浓度通常升高，而患有弥散性血管内凝血（DIC）的癌症患者血浆纤维蛋白原浓度较低。高钙血症可能是骨转移的后果。肿瘤在一些患者中可能导致肾病综合征。应通过显微镜检查积液以寻找恶性肿瘤的迹象。血清酶水平升高在肿瘤性疾病中并无特异性。
