Radovanović Z, Naumović T, Velimirović D
Oncology. 1984;41(6):396-8. doi: 10.1159/000225862.
In a Balkan nephropathy endemic area, 5 siblings developed haematuria over a period of 10 years. 4 of them were operated on and pathohystological examination revealed papillary transitional cell tumours of the renal pelvis and/or ureters. Both these tumours and the Balkan nephropathy affected only 1 generation of the family members. This fact, as well as the other relevant evidence, indicated that environmental factors played an important role in the process of carcinogenesis.
在一个巴尔干肾病流行地区，5名兄弟姐妹在10年期间出现血尿。其中4人接受了手术，病理组织学检查发现肾盂和/或输尿管的乳头状移行细胞肿瘤。这些肿瘤和巴尔干肾病仅影响了家族中的一代人。这一事实以及其他相关证据表明，环境因素在致癌过程中起重要作用。
