Menter M A, Whiting D A, McWilliams J
Pediatr Dermatol. 1984 Jul;2(1):8-12. doi: 10.1111/j.1525-1470.1984.tb00434.x.
During a three-and-one-half-year period, 54 children aged 1 to 16 years, all of whom had resistant psoriasis, were seen at a day-care center. The female: male ratio was 3:2. In 74% of the patients, the onset of psoriasis occurred when they were below 10 years of age. Papules and plaques occurred in 78% of cases, guttate lesions in 16%, and nail involvement in 21%. A family history of psoriasis was present in 69% of cases, preceding upper respiratory tract infections occurred in 35%, and prior cradle cap and/or diaper rash in 50%. In the day-care center, Goeckerman therapy was given to 31 children. The average duration of treatment was 12 days, producing maximum clearing of over 90% in 64% of patients, with substantial improvement in the remainder. After three months, the psoriasis in 83% of these patients was over 90% clear; 43% showed maximum clearing at one year. Two patients were treated with anthralin and ultraviolet light alone, one with good results. One patient with nail psoriasis alone was not treated. The remaining 20 patients were either unable to attend for treatment at the center or had less extensive psoriasis. Home treatment was prescribed for them, with less satisfactory results.
在三年半的时间里，一家日托中心接待了54名年龄在1至16岁之间、均患有顽固性银屑病的儿童。男女比例为3:2。74%的患者在10岁之前就出现了银屑病。78%的病例出现丘疹和斑块，16%出现点滴状皮损，21%出现指甲受累。69%的病例有银屑病家族史，35%在发病前有上呼吸道感染，50%有过摇篮帽和/或尿布疹病史。在日托中心，31名儿童接受了戈克曼疗法。平均治疗时长为12天，64%的患者实现了超过90%的最大程度皮损清除，其余患者也有显著改善。三个月后，这些患者中83%的银屑病皮损清除率超过90%；43%在一年时实现了最大程度清除。两名患者仅接受了蒽林和紫外线治疗，其中一名效果良好。一名仅患指甲银屑病的患者未接受治疗。其余20名患者要么无法到中心接受治疗，要么银屑病病情较轻。为他们开了家庭治疗方案，但效果不太令人满意。
