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孕期单侧卵巢切除对小鼠胎盘和胎儿生长的影响。

The effects of unilateral ovariectomy during pregnancy on placental and fetal growth in mice.

作者信息

Dewar A D, Ghione R M, Humphreys E M, Prescott R J

出版信息

Placenta. 1984 Jul-Aug;5(4):323-7. doi: 10.1016/s0143-4004(84)80013-2.

DOI:10.1016/s0143-4004(84)80013-2
PMID:6504862
Abstract

A comparison between placental weight and number of fetuses in normal mice and those in mice unilaterally ovariectomized on the sixth day of pregnancy, revealed a relative hypertrophy of the placentae of the latter group, with a predominance of the effect in litter sizes of five or less. The weights of the fetuses in the unilaterally ovariectomized group were not significantly different from those of the controls, thus affording no evidence of a causal connection between fetal weight and gross placental weight.

摘要

对正常小鼠以及在妊娠第6天进行单侧卵巢切除的小鼠的胎盘重量与胎儿数量进行比较,结果显示,后一组小鼠的胎盘相对肥大,在产仔数为5只及以下时这种影响更为明显。单侧卵巢切除组的胎儿重量与对照组相比无显著差异,因此没有证据表明胎儿体重与胎盘总重量之间存在因果关系。

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