Pushkar' N S, Makedonskaia V A, Utevskiĭ A M, Chuĭko V A, Karpenko L G
Probl Endokrinol (Mosk). 1984 Sep-Oct;30(5):42-6.
To treat postoperative hypothyrosis, use was made of implantation of autologous thyroid tissue preserved and stored for 4 to 12 months before patients developed hypothyrosis. It was established that the treatment was followed by an increase in 131I accumulation in the body at the expense of its accumulation by the implant and stimulation of the process in the stump. This was paralleled by a considerable rise in T3 and T4 and reduction in TTH in the patients' blood. The patients substantially improved while the manifestations of hypothyrosis disappeared. The effects detected could be seen throughout the whole observation period (up to 18 months). The patients did not require any additional drug treatment. The data provided attest to the efficacy of autoimplantation of cryopreserved thyroid parenchyma for the treatment of postoperative hypothyrosis.
为治疗术后甲状腺功能减退症,采用了植入自体甲状腺组织的方法,该组织在患者出现甲状腺功能减退症之前已保存并储存4至12个月。结果表明,治疗后体内131I的蓄积增加,这是以植入物对其蓄积以及对残端过程的刺激为代价的。与此同时,患者血液中的T3和T4显著升高,TTH降低。患者病情大幅改善,甲状腺功能减退症的症状消失。在整个观察期(长达18个月)内都能看到所检测到的效果。患者无需任何额外的药物治疗。所提供的数据证明了冷冻保存的甲状腺实质自体植入治疗术后甲状腺功能减退症的有效性。