Fuller R W, Snoddy H D
Res Commun Chem Pathol Pharmacol. 1984 Oct;46(1):151-4.
Ketanserin, given i.p. 1 hr before quipazine, antagonized the elevation of serum corticosterone by quipazine in rats. The relatively low ED50 value of ketanserin (0.9 mg/kg) supports other literature data showing that ketanserin is selective for the 5HT2 subtype of serotonin receptors, the data also suggest that 5HT2 receptors are involved in the elevation of serum corticosterone by the serotonin agonist, quipazine.
在给大鼠注射喹哌嗪前1小时腹腔注射酮色林，可拮抗喹哌嗪引起的大鼠血清皮质酮升高。酮色林相对较低的半数有效剂量（ED50）值（0.9毫克/千克）支持了其他文献数据，表明酮色林对5-羟色胺受体的5HT2亚型具有选择性，这些数据还表明5HT2受体参与了血清素激动剂喹哌嗪引起的血清皮质酮升高。
