Roux E, Nicole A, Capitaine Y
Schweiz Med Wochenschr. 1984 Oct 20;114(42):1470-2.
Prescription of so inoffensive-seeming and common a treatment as mucilaginous laxative may have major (if rare) side effects, such as sudden esophageal obstruction. This usually occurs in old people who do not take enough water with the laxative and who may have minor esophageal pathology such as motility disorders or epibronchic diverticulum. The usually typical symptoms are sudden onset, with retrosternal pain, dysphagia or total aphagia, alimentary vomiting and pseudohypersialorrhea. Diagnosis is always by radiography and endoscopy. Radiography must be performed with gastrografin, due to the risk of bronchoaspiration or esophageal fissure. Endoscopy may demonstrate the mucilagenous mass responsible for the obstruction and in most cases restore patency of the esophagus. This technique should always be attempted, if necessary several times, before resorting to surgery. The authors stress that in patients with a risk of esophageal obstruction, such as old people with esophageal disorders, it is essential to explain clearly to the patient that the laxative must be taken with a sufficient quantity of liquid.
开具看似无害且常见的黏液性缓泻剂治疗可能会有严重（尽管罕见）的副作用，比如突发食管梗阻。这通常发生在服用缓泻剂时饮水不足且可能有轻微食管病变（如动力障碍或支气管上憩室）的老年人身上。通常典型的症状是突然发作，伴有胸骨后疼痛、吞咽困难或完全不能吞咽、消化性呕吐和假性唾液分泌过多。诊断总是通过放射检查和内镜检查。由于存在支气管误吸或食管破裂的风险，必须使用泛影葡胺进行放射检查。内镜检查可能会显示造成梗阻的黏液团块，并且在大多数情况下可恢复食管通畅。在采取手术治疗之前，应始终尝试这种技术，如有必要可进行多次。作者强调，对于有食管梗阻风险的患者，如患有食管疾病的老年人，必须向患者清楚解释服用缓泻剂时必须饮用足够的液体。
