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系谱和族谱过程及其在群体遗传学模型中的应用。

Line-of-descent and genealogical processes, and their applications in population genetics models.

作者信息

Tavaré S

出版信息

Theor Popul Biol. 1984 Oct;26(2):119-64. doi: 10.1016/0040-5809(84)90027-3.

Abstract

A variety of results for genealogical and line-of-descent processes that arise in connection with the theory of some classical selectively neutral population genetics models are reviewed. While some new results and derivations are included, the principle aim is to demonstrate the central importance and simplicity of genealogical Markov chains in this theory. Considerable attention is given to "diffusion time scale" approximations of such genealogical processes. A wide variety of results pertinent to (diffusion approximations of) the classical multiallele single-locus Wright-Fisher model and its relatives are simplified and unified by this approach. Other examples where such genealogical processes play an explicit role, such as the infinite sites and infinite alleles models, are discussed.

摘要

本文回顾了与一些经典选择中性群体遗传学模型理论相关的系谱和世系过程的各种结果。虽然包含了一些新的结果和推导,但主要目的是证明系谱马尔可夫链在该理论中的核心重要性和简单性。本文对这类系谱过程的“扩散时间尺度”近似给予了相当多的关注。通过这种方法,与经典多等位基因单基因座赖特 - 费希尔模型及其相关模型(的扩散近似)相关的各种结果得到了简化和统一。还讨论了这类系谱过程发挥明确作用的其他例子,如无限位点模型和无限等位基因模型。

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