Gammage M D, Littler W A, Abrams L D
Thorax. 1984 Nov;39(11):868-71. doi: 10.1136/thx.39.11.868.
Surgical repair of the mitral valve was undertaken in two young female patients during the active phase of bacterial endocarditis to eradicate persistent infection. Operation resulted in rapid resolution of infection with good haemodynamic results in both patients. A mitral valve prosthesis has the disadvantage for children of needing replacement because of growth, and for young women of leading to problems in pregnancy because of the need for lifelong anticoagulant treatment. Thus repair rather than replacement of the mitral valve should be considered in patients, especially young women, presenting with mitral regurgitation in these circumstances.
两名年轻女性患者在细菌性心内膜炎活动期接受了二尖瓣手术修复，以根除持续感染。手术使两名患者的感染迅速得到解决，血流动力学结果良好。二尖瓣人工瓣膜对儿童有因生长需要更换的缺点，对年轻女性有因需要终身抗凝治疗而导致妊娠问题的缺点。因此，在这些情况下出现二尖瓣反流的患者，尤其是年轻女性，应考虑修复而非置换二尖瓣。
