Gudima G O, Vorob'ev I A, Chentsov Iu S
Tsitologiia. 1984 Sep;26(9):1002-7.
Different motile blood cells behave in a different way upon spreading on the glass surface. Macrophages pass through all the stages of spreading described for fibroblasts (Vasiliev, Gelfand, 1976); granulocytes are polarized after a short staying in badly spread conditions, lymphocytes are polarized immediately after setting of the glass surface. In relation to the leading edge and the cell nucleus, centrioles in the described cell types are located differently. In macrophages they are mainly in the front or on one side of the nucleus, in granulocytes they lie within the ring-like nucleus, in lymphocytes they are strictly located behind the nucleus in the uropode. In all the cases, however, centrioles are localized in the central region of the cytoplasm. Their location does not appear to be connected with the movement direction of blood cells. The distal ends of the active centrioles are faced to the upper cell surface in the examined cells. It is suggested that the centriole can distinguish the free cell surface and the surface associated with the substrate.
不同的可移动血细胞在玻璃表面铺展时表现各异。巨噬细胞经历了成纤维细胞铺展所描述的所有阶段（瓦西里耶夫、盖尔方德，1976年）；粒细胞在短暂处于铺展不良状态后会发生极化，淋巴细胞在接触玻璃表面后立即极化。在所描述的细胞类型中，中心粒相对于前沿和细胞核的位置有所不同。在巨噬细胞中，它们主要位于细胞核的前方或一侧，在粒细胞中它们位于环状细胞核内，在淋巴细胞中它们严格位于尾足细胞核的后方。然而，在所有情况下，中心粒都位于细胞质的中心区域。它们的位置似乎与血细胞的移动方向无关。在所研究的细胞中，活跃中心粒的远端面向细胞上表面。有人认为，中心粒能够区分游离的细胞表面和与底物相关的表面。
