Maenhout D, Ducatelle R, Coussement W, Nuytten J, Thoonen H, Hoorens J
Vet Rec. 1984 Oct 20;115(16):407-10. doi: 10.1136/vr.115.16.407.
Clinical and pathological data of a recently discovered neurological disorder in young calves were studied. The symptoms were those of a paralysis of the nervus facialis and a dysfunction of the nervus vestibulocochlearis. Macroscopically, space occupying lesions were found at the roots of these two cranial nerves and in some cases further on their course into the os petrosum. On histological examination, these legions contained multiple nodules with mainly histiocytic cells, some plasma cells and multinucleated giant cells. Around these nodules, dense bands of connective tissue with fusocellular fibroblasts, some plasma cells and small blood capillaries were present. The nodular lesions were usually in close contact with the nerve. Ultrastructurally, a variety of cells, predominantly histiocytes and some plasma cells, were seen next to Schwann cells which contained degenerating axons.
对最近发现的幼龄犊牛神经疾病的临床和病理数据进行了研究。症状表现为面神经麻痹和前庭蜗神经功能障碍。宏观上，在这两条颅神经的根部发现占位性病变，在某些情况下，病变还沿其行程延伸至岩骨。组织学检查显示，这些病灶包含多个结节，主要由组织细胞、一些浆细胞和多核巨细胞组成。在这些结节周围，有密集的结缔组织带，其中有梭形细胞成纤维细胞、一些浆细胞和小血管。结节性病变通常与神经紧密相连。超微结构上，在含有变性轴突的施万细胞旁可见多种细胞，主要是组织细胞和一些浆细胞。
